What Happens If Semaglutide Is Not Refrigerated

What Happens If Semaglutide Is Not Refrigerated?

What Happens If Semaglutide Is Not Refrigerated
What Happens If Semaglutide Is Not Refrigerated

Semaglutide, a mediction used to manage type 2 diabetes, is often a subject of concern when it comes to storage conditions. This article aims to provide a comprehensive understanding of what happens if semaglutide is not refrigerated, and why it is crucial to store it correctly.

Understanding Semaglutide

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which helps control blood sugar levels in people with type 2 diabetes. It is comonly marketed under the brand names Ozempic and Rybelsus. The medication is typically administered via injection or orally.

Importance of Refrigeration

Like many medications, semaglutide needs to be stored under specific conditions to maintain its efficacy. According to the manufacturer’s instrucions, unopened semaglutide should be stored in a refrigerator betwen 2°C and 8°C (36°F and 46°F). This is to ensure the stability of the medication and prevent it from degrading.

What Happens If Semaglutide Is Not Refrigerated?

If semaglutide is not refrigerated, it may lose its effectiveness over time. Exposure to temperatures above the recommended range can cause the medication to degrade, reducing its ability to control blood sugar levels effectively. This could potentially lead to uncontrolled blood sugar levels in people with type 2 diabetes, increasing the risk of diabetes-related complications.

Does Semaglutide Have to Be Refrigerated?

While unopened semaglutide should always be refrigerated, once opened, the medication can be stored at room temperature (up to 30°C or 86°F) for up to 56 days. However, it should be kept away from direct heat and light. It is also important to note that the medication should not be frozen. If it has been frozen, it should be discarded.

Replacement Parts of Semaglutide

As semaglutide is a medication, it does not have replacement parts. However, if you are using the injectable form of semaglutide, you may need to replace the needles regularly. Always use a new needle for each injection to prevent contamination and infection.

When to Contact Authorized Service

If you have any concerns about your semaglutide medication, such as its storage conditions or its effectiveness, it is recommended to contact the manufacturer or your healthcare provider. They can provide accurate information and guidance based on your specific situation.

For those living in America, there are service centers in many provinces. You can find the nearest service center by calling the call center specified on the company’s official website.


Proper storage of semaglutide is crucial to maintain its effectiveness in controlling blood sugar levels. While it should be refrigerated before opening, it can be stored at room temperature once opened. However, it should never be exposed to extreme temperatures or direct sunlight. If you have any concerns about your medication, do not hesitate to contact your healthcare provider or the manufacturer.

Note: The information provided in this article is collected from the internet and may contain inaccuracies. For the most accurate and up-to-date information, please visit the official website of the manufacturer. The site owner does not bear any responsibility for any incorrect information or application.

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